Research Articles
Beyond Publication: Implementing FAIR Principles to Ensure Reproducible AI/ML Models in Biomedical Research
This article provides a comprehensive guide for researchers and drug development professionals on applying the FAIR (Findable, Accessible, Interoperable, Reusable) principles to computational models.
From Prediction to Proof: A Practical Guide to Validating Systems Biology Models in Biomedical Research
This article provides a comprehensive roadmap for researchers, scientists, and drug development professionals to bridge the gap between computational predictions and experimental reality in systems biology.
Evolution Strategies vs Simulated Annealing: A Performance Comparison for Scientific Optimization in Drug Discovery
This article provides a comprehensive, practical comparison of Evolution Strategies (ES) and Simulated Annealing (SA) as global optimization techniques, specifically tailored for researchers and professionals in computational biology and drug...
Evolution Strategies in Action: Revolutionizing Biochemical Parameter Estimation for Drug Discovery
This article provides a comprehensive exploration of Evolution Strategies (ES) for biochemical parameter estimation, a critical bottleneck in systems biology and drug development.
Beyond Point Estimates: Why Prediction Intervals Are Critical for Reliable Biological Network Optimization
This article provides a comprehensive guide for researchers on evaluating and utilizing prediction intervals in biological network optimization.
Multi-Omics Integration for Breast Cancer Subtyping: A 2024 Guide to Methods, Challenges, and Clinical Translation
This comprehensive review analyzes the current state and future potential of multi-omics data integration for refining breast cancer subtype classification.
From Cells to Organisms: Understanding and Harnessing Emergent Properties in Biological Systems for Biomedical Research
This article provides a comprehensive analysis of emergent properties in biological systems, a foundational concept where complex behaviors and functions arise from the interactions of simpler components.
Mastering Spatial Biology: A Complete EDA Workflow Guide for Visualizing Spatial Transcriptomics Data
This article provides a comprehensive, intent-driven guide to the essential Exploratory Data Analysis (EDA) workflow for spatial transcriptomics visualization.
EDA vs. Confirmatory Analysis: Mastering Both Phases in Modern Biological Research & Drug Development
This article provides a comprehensive guide for researchers, scientists, and drug development professionals on the distinct yet complementary roles of Exploratory Data Analysis (EDA) and confirmatory data analysis in biological...
Mastering Exploratory Data Analysis (EDA) for Gene Expression Data: A Step-by-Step Guide for Biomedical Researchers
This comprehensive guide details essential Exploratory Data Analysis (EDA) techniques for gene expression datasets, targeting researchers, scientists, and drug development professionals.